Global Animal Model Market is expected to hold a value of about USD 3,632.48 Million by 2027 and is projected to register a CAGR of 7.8% from 2020 to 2027.
Animal model is a non-human species that are used in medical research as it shows similar aspects of diseases that are found in humans. Animal models are majorly used to test the effectiveness of the treatment cycle and efficacy of a drug for the particular disease condition.
There are a large number of different market players for an animal model that dominates the market, which includes Janvier Labs, GenOway S.A., and Envigo. The companies are involved in launching new products, technologies, and undergo strategic collaboration to develop healthcare produces. For instance, in March 2020, Transgenic, Inc. entered into a licensing agreement with Kyoto University on the manufacturing and distribution of transgenic mouse models.
Segmentation
By Animal Type
Mice: It is the most commonly used animal model used to study human disease. Mice are highly preferred in research activities they are biologically very similar to humans and possess the same disease as humans such as Hantavirus. Mice are highly preferred to study diseases such as hypertension and atherosclerosis.
Rats: Rats are considered as the ideal animal model and most widely used in the laboratories. In animal type rat holds the largest market share as it is used in different research activities such as immunology research, diabetes research, and others. Additionally, rats are found to be more advance in cognition and capable of learning different types of tasks that helped cognitive research.
Pigs: Pigs also known as swine are considered as the best model for clinical validation of drugs and medical devices. The pigs are similar to humans in terms of genetics, physiological, physiology, or anatomy. The growing need for swine models in research activity is increasing segmental growth. The National Swine Resource and Research Center located in the US is to provide high-quality biomedical pig models for research activity.
Rabbits: Rabbits are preferred as they are easy to handle and cost-effective. In comparison to other animals such as monkeys or mice, rabbits have faster bone turnover and skeletal changes, because of this property it is largely used in the surgical examination. Rabbits are used for the screening implant material before testing it on big animal models.
Others: The segment includes a monkey, horse, cat, and other animals.
By Technology
CRISPR: It is the most common technique used in animal modeling at different stages from
embryonic to organismal level in different species. CRISPR is used to edit or manipulate the DNA sequence. Charles River an American company offers CRISPR rats and mice using genetic transfer into embryos or embryonic stem cells. CRISPR technology includes different methods such as:
Microinjection: Microinjection is used to create transgenic organisms by injecting genetic material into the nucleus of a fertilized oocyte. This technique is used to study the character of genes using mouse animal models.
Electroporation: It is a technique through with the molecules can be transferred into the cell wall by using electric field pulses. By using this technique, the DNA molecules can be transferred into the cell which can be used to develop specific animal models.
Others: The other technology includes vector or virus-mediated gene transfer, calcification method, and others.
By Application
Research and Development: Animal models are used as the guinea pig for research activities for various diseases such as cardiovascular, infectious diseases, metabolic diseases, immunological diseases, cancer, diabetes, genetic diseases, neurological diseases, and others. Also, the companies are developing humanized animal models to understand the disease characteristics. For instance, in March 2020. Transgenic, Inc. developed a mouse with humanized exon for research on novel coronavirus infection (COVID-19). The development of these animal models will help to understand the infection mechanism and help to develop treatment methods.
Production and Quality Control: In in-vitro diagnostic tests the animal models are used to check the quality of the product. Also, the increasing demand for targeted therapy and personalized medicine especially to treat cancer patients support the market growth.
By End-User
Pharmaceutical Companies: Pharmaceutical companies are estimated to be the largest market
owing to the increased adoption of animal models in drug discovery & development by pharmaceuticals and biotechnology companies. It appears that there has been widespread acceptance of the potential value of animal models. In April 2017, Charles River Laboratories announced the launch of a triple-immunodeficient mouse model for oncology research
Contract Research Organizations: There has been an increasing preference for contract research organizations by healthcare companies at different stages of manufacturing. The majority of healthcare companies outsource their research activities to contract research organizations to reduce the cost of production and time. In the global market, CROs are preferred for customized research by the drug manufacturing companies which drives segmental growth.
Research Institutes: Research institutes are estimated to be the fastest-growing segment in the global animal model market. The increasing preference of animal models as a base material for their research activities which boosts market growth.
Educational Institutes: Academic and educational institutes also use the preserved animal cell models to study and understand the toxicity behavior of drugs.
Key Players