Cell Culture Protein Surface Coating Market Size Report, 2024-2033
The global cell culture protein surface coatings market size was exhibited at USD 826.80 million in 2023 and is projected to hit around USD 3,433.16 million by 2033, growing at a CAGR of 15.30% during the forecast period of 2024 to 2033.
Key Takeaways:
Cell Culture Protein Surface Coatings Market Report Scope
| Report Coverage | Details |
| Market Size in 2024 | USD 953.30 Million |
| Market Size by 2033 | USD 3,433.16 Million |
| Growth Rate From 2024 to 2033 | CAGR of 15.30% |
| Base Year | 2023 |
| Forecast Period | 2024-2033 |
| Segments Covered | Coating Type, Protein Source, Region |
| Market Analysis (Terms Used) | Value (US$ Million/Billion) or (Volume/Units) |
| Regional Scope | North America; Europe; Asia Pacific; Central and South America; the Middle East and Africa |
| Key Companies Profiled | Thermo Fisher Scientific, Inc.; Corning Incorporated; Merck KGaA; Eppendorf SE; Sartorius AG; Greiner Bio-One International GmbH; PerkinElmer, Inc.; ZenBio, Inc.; Kollodis BioSciences, Inc.; Viogene |
The increasing interest of scientists and biotechnology companies in stem cell research is a major factor driving the industry growth. Cell culture protein surface coating provides improved development and cell adhesion in in-vitro cell culture. Thus, the demand for these products is increasing, thus creating revenue generation opportunities. A stem cell is a very effective and promising therapy to treat several severe diseases including neurological diseases, cancer, Cardiovascular Diseases (CVDs), and cell deficiency.
For instance, Parkinson's and Alzheimer's disease can be treated by replacing damaged cells and tissues. In the context of COVID-19, various government organizations, research institutes, and pharmaceutical & biotech firms are focusing on rapid and effective technologies for developing vaccines/novel therapeutics and diagnosis of COVID-19 to overcome the situation. For instance, researchers from UVE (Unité des Virus Émergents) screened 1,520 USFD-approved drugs for their anti-viral properties using Caco-2 and VeroE6 immortalized cell lines. From this study, researchers recognized 90 compounds spanning distinct drug categories, such as proton pump inhibitors and antibiotics that might be therapeutically relevant to treat COVID-19.
Similarly, researchers from the Institute for Molecular Medicine Finland made use of VeroE6 cell lines and found that a combination of host-directed amodiaquine and orally available virus-directed nelfinavir unveiled the finest therapeutic effects against COVID-19 across 136 broad range antiviral products. Such developments significantly increased the demand for culture products during the COVID-19 pandemic. The rising interest of researchers and biotechnology companies in stem cell research is one of the key factors driving the industry's growth. Stem cells have become a potential tool for the treatment of several disorders, such as osteoarthritis, heart failure, and eye diseases.
Regenerative medicine has revolutionized research in science and technology by growing entirely new organs and tissues outside the body by taking cells from patients. This would further increase the demand for regenerative medicine for the treatment of diseases. With constant development in therapies, several new advanced cell culture protein surfaces have emerged. Advancements in the research and development field would further fuel industry growth in the coming years. The protein surfaces offer better growth and adhesion in cell culture. Gelatin is usually used in the culture of muscle, Embryonic Stem (ES) cells, and vascular endothelial cells, among others.
Corning Inc., one of the leading players, offers a wide range of cell culture protein surfaces and substrates, which enable cell attachment under difficult conditions. For instance, the company offers BioCoat Gelatin culture ware, which offers attachment and growth-promoting substrate for the culture. Moreover, in the past few years, cell culture has evolved and is widely used as a bioproduction and research tool. The protein surfaces used for growing cells have progressed rapidly, as the need for researchers has changed. Several breakthrough studies have helped with the advancement of the culture medium, resulting in a significant rise in the use of cell culture.
The other drivers include the growing demand for targeted therapy and protein therapeutics along with an increasing preference for 2D and 3D cell cultures. 3D cell culture is a process of growing biological cells in a controlled condition, where cells could interact with the surrounding cells across all dimensions. The protein-coated instruments offer a 3D microenvironment to attain proper proliferation and cell adhesion. For instance, Agilent Technologies offers automated imaging tools that could provide significant information to improve routine culture techniques and increase the reproducibility and effectiveness of downstream cell-based assays.
Segments Insights:
Coating Type Insights
Based on coating types, the global industry has been further segmented into pre-coating and self-coating. In 2023, the self-coating segment dominated the global industry and accounted for the highest share of around 65.0% of the overall revenue. The rising investment in research and development is a key factor boosting segment growth. The biotechnology and biopharmaceutical companies are focusing on the production of monoclonal antibodies, protein therapeutics, induced pluripotent stem cell research, and cryobanking. Thus, the demand for self-coating is also expected to remain high during the study period.
On the other hand, the pre-coating segment is expected to register the fastest growth rate during the forecast period. This segment is further classified into multiwall/microwell plates, flasks, Petri dishes, slides, and cover slips. The precoated culturewares provides several advantages, such as it is ready-to-use, saving time, delivering consistent quality, and improving isolation and cultivation. Thus, the popularity of pre-coating culturewares is increasing. This, in turn, is projected to boost the growth of the pre-coating segment.
Protein Source Insights
Based on protein sources, the global industry has been further categorized into animal-derived, human-derived, synthetic, and plant-derived proteins. The animal-derived material segment dominated the global industry in 2023 and accounted for the highest share of 40.16% of the overall revenue. The major application of these products in the production of biopharmaceuticals including monoclonal antibodies and recombinant proteins is the most predominant factor contributing to its highest share. On the other hand, the demand for human-derived protein products is also high due to their large application in insulin production.
The increasing incidence of diabetes drives the demand for insulin. Thus, the rising incidence of diabetes boosts the growth of the human-derived protein segment. On the other hand, the synthetic material segment is expected to exhibit the fastest growth rate during the forecast period. The growing demand for animal-free components is a prime factor attributing to the growth of this segment. Ethical and religious constraints on the application of animal-derived protein propel the adoption of synthetic protein coatings.
Regional Insights
North America dominated the overall industry and accounted for the largest share of 40.0% in 2023. The highly developed healthcare & research infrastructure and focus on drug discovery in the region have fueled the region’s growth. The U.S. dominated the regional market of North America owing to the rapid technological advancements, increasing approval for cell culture-based vaccines, growth in pharmaceutical and biotechnology industries, strong government support, high funding in cell-based research, and growing incidence of diseases, such as cancer. For instance, in May 2023, Blue Water Vaccines, Inc. collaborated with the multidisciplinary Center for Research and Development in Immunobiologics, which aims to develop influenza vaccine candidates based on cell culture and adjuvant formulation-based vaccines.
Asia Pacific is expected to register the fastest CAGR during the study period due to untapped opportunities in the region. China is anticipated to witness significant growth in the coming years owing to the presence of several biopharmaceutical companies and clinical research organizations in the country working towards drug discovery and development. The untapped opportunities in the country are attracting international players to invest in the country’s market. For instance, in October 2020, Merck KGaA collaborated with D1Med a Shanghai-based biopharmaceutical company, that aims to advance the 3D cell culture technology in China, which could be used in the drug discovery process. Moreover, with favorable government policies and growing R&D investments, the country is witnessing a surge of innovative biotech and pharma companies.
Some of the prominent players in the Cell culture protein surface coatings market include:
Segments Covered in the Report
This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Nova one advisor, Inc. has segmented the global cell culture protein surface coatings market.
Coating Type
Protein Source
By Region
Chapter 1 Methodology And Scope
1.1 Research Methodology
1.2 Research Assumptions
1.2.1 Estimates And Forecast Timeline
1.3 Information Procurement
1.3.1 Purchased Database
1.3.2 Internal Database
1.3.3 Secondary Sources
1.3.4 Primary Research
1.3.5 Sample Size For The Study On Cell Culture Protein Surface Coating Market:
1.3.5.1 Primary Sources:
1.3.5.2 Details Of Primary Research
1.3.5.3 Secondary Data Sources:
1.4 Information Or Data Analysis
1.4.1 Data Analysis Models
1.5 Market Formulation & Validation
1.6 Market Model
1.7 Objectives
1.7.1 Objective 1:
1.7.2 Objective 2:
Chapter 2 Executive Summary
2.1 Market Snapshot
2.2 Segment Snapshot
2.3 Competitive Landscape Snapshot
Chapter 3 Market Variables, Trends, And Scope
3.1 Market Segmentation And Scope
3.2 Market Lineage Outlook
3.2.1 Parent Market Outlook
3.2.2 Related/Ancillary Market Outlook
3.3 Penetration And Growth Prospect Mapping
3.4 Market Dynamics
3.4.1 Market Drivers Analysis
3.4.1.1 Increasing Investments In Biopharmaceutical R&D
3.4.1.2 Expansion Of Biosimilars And Biologics
3.4.1.3 Rising Adoption Of Synthetic Protein Surface Coating
3.4.2 Market Restraint Analysis
3.4.2.1 Ethical Issues Concerning Use Of Animal-Derived Products
3.4.2.2 Stringent Regulatory Guidelines
3.4.3 Market Opportunity Analysis
3.4.3.1 Growth In Stem Cell Research
3.4.3.2 Emerging Cell Culture Technologies For Cell-Based Vaccines
3.5 Market Trends And Outlook
3.6 Business Environment Analysis
3.6.1 Swot Analysis: By Factor (Political & Legal, Economic And Technological)
3.6.2 Porter’s Five Forces Analysis
3.7 Recent Developments And Impact Analysis, By Key Market Participants
3.7.1 Major Deals And Strategic Alliances Analysis
3.7.1.1 Mergers And Acquisitions
3.7.1.2 Licensing And Partnerships
3.8 Covid-19 Impact Analysis
Chapter 4 Coating Type Business Analysis
4.1 Cell Culture Protein Surface Coating Market: Coating Type Movement Analysis, 2024 & 2033
4.2 Self-Coating
4.2.1 Self-Coating Market Estimates And Forecasts, 2021 - 2033
4.3 Pre-Coating
4.3.1 Pre-Coating Market Estimates And Forecasts, 2021 - 2033
4.3.1.1 Multiwall/Microwell Plates
4.3.1.1.1 Multiwall/Microwell Plates Market Estimates And Forecasts, 2021 - 2033
4.3.1.2 Petri Dishes
4.3.1.2.1 Petri Dishes Market Estimates And Forecasts, 2021 - 2033
4.3.1.3 Flasks
4.3.1.3.1 Flasks Market Estimates And Forecasts, 2021 - 2033
4.3.1.4 Slides
4.3.1.4.1 Slides Market Estimates And Forecasts, 2021 - 2033
4.3.1.5 Cover Slips
4.3.1.5.1 Cover Slips Market Estimates And Forecasts, 2021 - 2033
Chapter 5 Protein Source Business Analysis
5.1 Cell Culture Protein Surface Coating Market: Protein Source Movement Analysis, 2024 & 2033
5.2 Animal-Derived Proteins
5.2.1 Animal-Derived Cell Culture Market Estimates And Forecasts, 2021 - 2033
5.3 Human-Derived Proteins
5.3.1 Human-Derived Proteins Market Estimates And Forecasts, 2021 - 2033
5.4 Synthetic Proteins
5.4.1 Synthetic Proteins Market Estimates And Forecasts, 2021 - 2033
5.5 Plant-Derived Proteins
5.5.1 Plant-Derived Proteins Market Estimates And Forecasts, 2021 - 2033
Chapter 6 Cell Culture Protein Surface Coating Market: Regional Estimates And Trend Analysis, By Coating Type & Protein Source
6.1 North America
6.1.1 Swot Analysis:
6.1.1.1 North America Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.1.2 U.S.
6.1.2.1 Key Country Dynamics
6.1.2.2 Regulatory Framework
6.1.2.3 Market Scenario
6.1.2.4 U.S. Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.1.3 Canada
6.1.3.1 Key Country Dynamics
6.1.3.2 Regulatory Framework
6.1.3.3 Market Scenario
6.1.3.4 Canada Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.2 Europe
6.2.1 Swot Analysis:
6.2.1.1 Europe Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.2.2 Germany
6.2.2.1 Key Country Dynamics
6.2.2.2 Regulatory Framework
6.2.2.3 Market Scenario
6.2.2.4 Germany Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.2.3 UK
6.2.3.1 Key Country Dynamics
6.2.3.2 Regulatory Framework
6.2.3.3 Market Scenario
6.2.3.4 UK Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.2.4 France
6.2.4.1 Key Country Dynamics
6.2.4.1 Market Scenario
6.2.4.2 France Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.2.5 Italy
6.2.5.1 Key Country Dynamics
6.2.5.2 Market Scenario
6.2.5.3 Italy Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.2.6 Spain
6.2.6.1 Key Country Dynamics
6.2.6.2 Market Scenario
6.2.6.3 Spain Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.2.7 Denmark
6.2.7.1 Key Country Dynamics
6.2.7.2 Market Scenario
6.2.7.3 Denmark Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.2.8 Sweden
6.2.8.1 Key Country Dynamics
6.2.8.2 Market Scenario
6.2.8.3 Sweden Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.2.9 Norway
6.2.9.1 Key Country Dynamics
6.2.9.2 Market Scenario
6.2.9.3 Norway Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.3 Asia Pacific
6.3.1 Swot Analysis:
6.3.1.1 Asia Pacific Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.3.2 China
6.3.2.1 Regulatory Framework
6.3.2.2 Disease Prevalence
6.3.2.3 China Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.3.3 Japan
6.3.3.1 Regulatory Framework
6.3.3.2 Disease Prevelance
6.3.3.3 Japan Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.3.4 India
6.3.4.1 Key Country Dynamics
6.3.4.2 Regulatory Framework
6.3.4.3 Disease Prevalence
6.3.4.4 India Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.3.5 South Korea
6.3.5.1 Regulatory Framework
6.3.5.2 Disease Prevalence
6.3.5.3 South Korea Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.3.6 Australia
6.3.6.1 Key Country Dynamics
6.3.6.2 Regulatory Framework
6.3.6.3 Disease Prevalence
6.3.6.4 Australia Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.3.7 Thailand
6.3.7.1 Key Country Dynamics
6.3.7.2 Market Scenario
6.3.7.3 Thailand Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.4 Latin America
6.4.1 Swot Analysis:
6.4.1.1 Latin America Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.4.2 Brazil
6.4.2.1 Regulatory Framework
6.4.2.2 Disease Prevalence
6.4.2.3 Brazil Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.4.3 Mexico
6.4.3.1 Regulatory Framework
6.4.3.2 Disease Prevalence
6.4.3.3 Mexico Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.4.4 Argentina
6.4.4.1 Regulatory Framework
6.4.4.2 Disease Prevalence
6.4.4.3 Argentina Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.5 Middle East And Africa
6.5.1 Swot Analysis:
6.5.1.1 Middle East And Africa Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.5.2 South Africa
6.5.2.1 Regulatory Framework
6.5.2.2 Disease Prevalence
6.5.2.3 South Africa Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.5.3 Saudi Arabia
6.5.3.1 Regulatory Framework
6.5.3.2 Disease Prevalence
6.5.3.3 Saudi Arabia Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.5.4 UAE
6.5.4.1 Regulatory Framework
6.5.4.2 Disease Prevalence
6.5.4.3 Uae Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
6.5.5 Kuwait
6.5.5.1 Key Country Dynamics
6.5.5.2 Market Scenario
6.5.5.3 Kuwait Cell Culture Protein Surface Coating Market Estimates And Forecasts, 2021 - 2033
Chapter 7 Competitive Landscape
7.1 Company Categorization
7.2 Company Market Share Analysis, 2024
7.3 Strategy Mapping
7.4 Company Profiles/Listing
7.4.1 Thermo Fisher Scientific, Inc.
7.4.1.1 Overview
7.4.1.2 Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
7.4.1.3 Product Benchmarking
7.4.1.4 Strategic Initiatives
7.4.2 Corning, Inc.
7.4.2.1 Overview
7.4.2.2 Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
7.4.2.3 Product Benchmarking
7.4.2.4 Strategic Initiatives
7.4.3 Merck KGAA
7.4.3.1 Overview
7.4.3.2 Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
7.4.3.3 Product Benchmarking
7.4.3.4 Strategic Initiatives
7.4.4 Eppendorf SE
7.4.4.1 Overview
7.4.4.2 Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
7.4.4.3 Product Benchmarking
7.4.4.4 Strategic Initiatives
7.4.5 Sartorius AG
7.4.5.1 Overview
7.4.5.2 Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
7.4.5.3 Product Benchmarking
7.4.5.4 Strategic Initiatives
7.4.6 Greiner Bio-One International GMBH
7.4.6.1 Overview
7.4.6.2 Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
7.4.6.3 Product Benchmarking
7.4.6.4 Strategic Initiatives
7.4.7 Perkinelmer, Inc.
7.4.7.1 Overview
7.4.7.2 Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
7.4.7.3 Product Benchmarking
7.4.7.4 Strategic Initiatives
7.4.8 Zenbio, Inc.
7.4.8.1 Overview
7.4.8.2 Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
7.4.8.3 Product Benchmarking
7.4.8.4 Strategic Initiatives
7.4.9 Kollodis Biosciences, Inc.
7.4.9.1 Overview
7.4.9.2 Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
7.4.9.3 Product Benchmarking
7.4.9.4 Strategic Initiatives
7.4.10 Viogene
7.4.10.1 Overview
7.4.10.2 Financial Performance (Net Revenue/Sales/EBITDA/Gross Profit)
7.4.10.3 Product Benchmarking
7.4.10.4 Strategic Initiatives
Cross-segment Market Size and Analysis for Mentioned Segments
Additional Company Profiles
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Additional Countries (Apart
From Mentioned Countries)
Country/Region-specific Report
Go To Market Strategy
Region Specific Market DynamicsRegion Level Market Share Import Export AnalysisProduction AnalysisOthers