Single-use Bioreactors Market Size, Share & Analysis Report, 2023-2032
The global Single-use Bioreactors market size was exhibited at USD 3.34 billion in 2022 and is projected to hit around USD 16.35 billion by 2032, growing at a CAGR of 17.21% during the forecast period 2023 to 2032.
Key Pointers:
Single-use Bioreactors Market Report Scope
|
Report Coverage |
Details |
|
Market Size in 2023 |
USD 3.91 Billion |
|
Market Size by 2032 |
USD 16.35 Billion |
|
Growth Rate from 2023 to 2032 |
CAGR of 17.21% |
|
Base year |
2022 |
|
Forecast period |
2023 to 2032 |
|
Segments covered |
Product, type, type of cell, molecule type, application, end-use, usage type, region |
|
Regional scope |
North America; Europe; Asia Pacific; Central and South America; the Middle East and Africa |
|
Key companies profiled |
Sartorius Stedim Biotech; Thermo Fisher Scientific; Danaher; Merck KgaA; Celltainer Biotech BV; Getinge AB; Eppendorf AG; Cellexus; PBS Biotech Inc.; Distek Inc.; ABEC; Able Corporation & Biott Corporation; G&G Technologies Inc.; Solida Biotech GmbH; Satake Chemical Equipment Mfg., Ltd.; Stobbe Pharma GmbH; bbi-biotech GmbH |
The rising demand for biopharmaceuticals, coupled with increasing investments in single-use technologies, the market for single-use bioreactors is expected to witness significant growth throughout the forecast period.
Furthermore, the COVID-19 outbreak has positively impacted the market for SUBs. The race to create an effective vaccine against the SARS-CoV-2 virus is being undertaken by numerous biopharmaceutical firms. As a result, the need for single-use bioreactors has drastically increased. For instance, in October 2020, ABEC supplied six 4,000 L single-use bioreactors to the Serum Institute of India, for the production of COVID-19 vaccines on a large scale at a reasonable cost.
The value of the product, the time required for product development and production, in addition to the criticality of the phase are now influencing the industry's propensity to employ single-use bioreactors. In addition, the medical industry has a significant demand for these single-use bioreactors. As a result, pharmaceutical companies use these reactors to make medicines without having to compromise on their quality.
The flexibility of using single-use bioreactors is one of their main benefits. The growing trend toward multi-drug facilities necessitates the manufacture of various medications utilizing the same facility, in the shortest amount of time, and for the least amount of money. Thus, it will increase the demand for single-use bioreactors and further fuel market growth.
Additionally, the market for SUBs is anticipated to increase quickly because of considerable prospects from emerging countries, the demand for customized medicine, and an anticipated rise in bio-similar production in the U.S. For instance, around USD 110 billion worth of biologics were anticipated to lose their patent protection by 2020. The demand for biosimilars is therefore expected to rise in the coming years as a result of mounting pressure to lower healthcare costs and regulatory certainty about biosimilars, further driving the market growth.
However, the administration of single-use bioreactors-related challenges and worries about leachable and extractable are most likely to impede the single-use bioreactors market's expansion over the anticipated time. The single-use bioreactors market is likely to benefit from new opportunities brought on by license termination and emerging markets. Despite this, the market is primarily driven by the growing single-use bioreactor usage among startups and small businesses, technological developments in SUBs, and the benefits offered by these products.
Additionally, SUBs have been used more frequently lately in contemporary biopharmaceutical operations. This is mainly because of their exceptional capacity to increase flexibility, decrease investment, and regulate operational expenses. Furthermore, single-use bioreactors have a wide range of uses in academic and industrial laboratories, including drug discovery, pharmaceutical, environmental, and life science research for the production of vaccines, antibodies, cell culture, and biofuels, among other things. Thus, it will increase demand and further boost market growth.
Product Insights
The single use bioreactor systems segment captured the largest market share of above 81.19% in 2022. Single-use bioreactor systems are widely used in biopharmaceutical manufacturing processes that require high product yield. The versatility, cost-effectiveness, and high mass production capability of single-use bioreactors would increase demand for the products leading to rapid market growth.
Furthermore, the rising demand for quick development, and greater production of new bio-therapeutics including vaccines, antibodies, enzymes, and hormones, in addition to an increase in the product quantities that can be produced in these bioreactors, contributes to the market's ongoing expansion. In addition, an increase in the focus of key manufacturers on offering small-scale bioreactors will fuel segment growth over the next few years.
Type Insights
Stirred tank bioreactors accounted for the largest share of 80.21% in 2022. The benefits offered by these bioreactors include good oxygen transfer and fluid mixing ability, easy scale-up, low operating costs, compliance with cGMP requirements & alternative impellers. These factors have led to the highest penetration of stirred tank bioreactors in the market.
The availability of wave-induced bioreactors will increase in the coming years, boosting the market growth. In addition, for the past ten years, Wave Biotech AG has sold the original wave SUBs BIOSTAT RM. In 2019, the business unveiled the second version, BIOSTAT RM II, which has more sophisticated features & offers enhanced control of temperature and driving system. The demand for wave-induced SUBs is anticipated to increase due to these manufacturing developments during the forecast period. Therefore, such type of advancements by the manufacturers will drive segmental growth in the forecast period.
Type of Cell Insights
The mammalian cells segment accounted for the largest share of 80.82% in 2022. This can be attributed to the significant penetration of this cell type in the creation of biopharmaceutical therapies and the commercial success of recombinant proteins made from mammalian cells. As per BioProcess International, 85.0% of biopharmaceutical candidates in clinical development are made using mammalian cell cultures.
Yeasts are dependable eukaryotic hosts for the synthesis of heterologous proteins and offer special benefits in the generation of therapeutic recombinants. Growing attention given by several scientists and research organizations to the use of yeast cells in clinical or therapeutic settings will drive market expansion during the projected timeframe. For instance, research published by NCBI in June 2021 examined cutting-edge techniques and approaches for synthesizing heterologous medicinal proteins from yeast genes.
Molecule Type Insights
The vaccines segment accounted for the largest share of 27.95% in 2022. This is majorly attributed to the COVID-19 outbreak, which has resulted in an urgent need for the development of virus vaccines. According to Bioplan Associates, the use of single-use systems in the commercial manufacturing of vaccines is anticipated to rise sharply. Many biopharmaceutical companies are actively engaged in the quick development of COVID-19 vaccines in response to the pandemic.
Additionally, the gene modified cells segment is expected to expand at the fastest CAGR of 18.14% during the review period. The growing field of cell and gene therapies is anticipated to accelerate the uptake of SUBs in this market. For instance, in January 2021, Sartorius and RoosterBio, Inc. teamed up to improve the production capabilities for gene and cell therapies. The partnership aims to increase the manufacturing of regenerative medicines. Such an ongoing and continuous increase in the adoption of single-use systems is anticipated to drive market growth.
Application Insights
In 2022, the research and development (R&D)/process development segment accounted for an 80.29% share of the market. Single-use bioreactor utilization in process development is a driving force behind market expansion. For instance, according to an article published in 2020 by American Pharmaceutical Review, the industry has employed about 71.2% of single-use bioreactors for process development.
Furthermore, every component of the bioprocessing sector uses single-use systems. According to the American Pharmaceutical Review, single-use system devices are used for clinical or process development in about 85.0% of the operations. This exhibits the majority of single-use bioreactors in both clinical manufacturing and R&D.
The bioproduction sector is expected to attain the fastest CAGR of 17.93% and is anticipated to see significant use of single-use bioreactors in the near future, due to the numerous benefits they provide. The use of disposable reactors, from the lab to the industrial, has increased as a result of significant developments in bioreactor designs, sensor systems, and stirring motors.
Usage Insights
The lab-scale production segment held the largest revenue share of 35.71% in 2022. In the biopharmaceutical business, disposable bioreactors are frequently employed in preclinical & clinical research. It is anticipated that growing single-use technology acceptance would have a substantial impact on segment growth in cell-based therapy research and vaccine production.
Throughout the forecast period, it is anticipated that the large-scale production category would experience significant expansion at a CAGR of 18.37%. This is due to the quickly expanding market demand for the commercial production of biopharmaceutical goods and the growth of manufacturing capacity to accommodate these demands. For instance, Wuxi Biologics introduced a 36,000L bio manufacturing line in February 2021, employing nine 4,000L single-use bioreactors.
In addition, to enable the scale-up, companies such as Thermo Fisher Scientific and ABEC launched large-volume single-use bioreactors in the market. In recent years, Thermo Fisher introduced its 5000-L single-use bioreactor and ABEC launched its 4000-L and 6000-L single-use bioreactors.
End-use Insights
The CMOs & CROs segment accounted for a significant share of 38.69% in 2022 and it is also expected to be the fastest-growing segment during the study period. The demand for supply production capacity as well as quick awareness campaign change-overs is more among CMOs. As a result, they use a broader range of single-use components and systems. With the increasing trend of outsourcing, CROs & CMOs are more likely to adopt single-use bioreactors.
On the other hand, pharmaceutical and biopharmaceutical companies are estimated to witness significant growth. According to estimates, 66.0% of biopharmaceutical companies use disposable bioreactors in their routine operations. Furthermore, strategic activities by key market players offer lucrative opportunities in the review period. For instance, BioCentriq and Pall Corporation worked together in July 2021 to clinically manufacture Zolgensma, an FDA-approved gene therapy, utilizing an iCELLis fixed bed bioreactor.
Regional Insights
North America dominated the regional market with a share of 34.33% in 2022. This is explained by the fact that the region has well-established biopharmaceutical companies and key operating players. Additionally, the region's increased production capacity has added to the market expansion. For instance, Thermo Fisher Scientific stated in September 2021 that it would build a new manufacturing facility specifically for single-use bioprocessing products.
Asia Pacific is estimated to witness the fastest CAGR of 17.63% throughout the forecast period. According to estimates, Asian businesses, including both domestic contenders and global behemoths, are building approximately half of all new bioprocessing facilities worldwide. In the near future, this is anticipated to significantly fuel single-use bioreactors market expansion in the Asia Pacific.
Some of the prominent players in the Single-use Bioreactors Market include:
Segments Covered in the Report
This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2018 to 2032. For this study, Nova one advisor, Inc. has segmented the global Single-use Bioreactors market.
By Product Scope
By Type
By Type of Cell
By Molecule Type
By Application
By Usage Type
By Region
Chapter 1 Methodology And Scope
1.1 Research Assumptions
1.2 Research Methodology
1.3 Information Procurement
1.3.1 Sample size for the study on single-use bioreactors market:
1.3.1.1 Primary Sources:
1.3.1.2 Secondary Data Sources:
1.4 Information or Data Analysis
1.5 Market Formulation & Validation
1.6 Global Market: CAGR Calculation
1.7 Objectives
1.7.1 Objective 1:
1.7.2 Objective 2:
Chapter 2 Executive Summary
2.1 Market Summary, 2023
2.2 Market Segmentation
Chapter 3 Market Variables, Trends, & Scope
3.1 Market Dynamics
3.1.1 Market Driver Analysis
3.1.1.1 Increasing adoption of SUBs among small companies and startups
3.1.1.2 Reduction in automation complexity
3.1.1.3 Reduction in energy and water consumption
3.1.1.4 Rising research in biopharmaceutical market
3.1.1.5 Technological advancements in SUBs
3.1.2 Market Restraint Analysis
3.1.2.1 Regulatory Concerns related to single-use bioreactors
3.1.3 Market Opportunity Analysis
3.1.3.1 Patent expiry
3.1.4 Market Challenge Analysis
3.1.4.1 Concerns on sterility with use of single-use bioreactors
3.1.4.2 Requirements for compatible and GMP certified sensors
3.1.4.3 Implementation in single-use bioreactors workflow
3.2 Penetration and Growth Prospect Mapping for Product, 2023
3.3 Impact of COVID-19 Pandemic On Global Single-Use Bioreactors Market
3.3.1 Short-term impacts
3.3.2 Long-term adaption
3.3.3 Supply-chain shortage
3.4 Business Environment Analysis
3.4.1 SWOT analysis; by factor (political & legal, economic, and technological)
3.4.2 Porter’s five forces analysis
Chapter 4 Competitve Landscape
4.1 Recent Developments and Impact Analysis by Key Market Participants
4.2 Company Mapping
4.3 List of Potential End Users
4.4 List of Emerging Players
4.5 Marker Differentiators
4.6 Competitive Dashboard Analysis
4.7 Regional Network Map
Chapter 5 Single-Use Bioreactors Market: Product Business Analysis
5.1 Single-use bioreactors Market: Product Movement Analysis
5.2 Single-use bioreactor systems
5.2.1 Single-use bioreactor systems market estimates and forecast, 2020 - 2032
5.2.2 UP TO 10L
5.2.2.1 Single-use bioreactor market estimates and forecast for systems upto 10L, 2020 - 2032
5.2.3 11 TO 100L
5.2.3.1 Single-use bioreactor market estimates and forecast for systems from 11 to 100L, 2020 - 2032
5.2.4 101 TO 500L
5.2.4.1 Single-use bioreactor market estimates and forecast for systems from 101 to 500L, 2020 - 2032
5.2.5 501 TO 1500
5.2.5.1 Single-use bioreactor market estimates and forecast for systems from 501 to 1500L, 2020 - 2032
5.2.6 ABOVE 1500L
5.2.6.1 Single-use bioreactor market estimates and forecast for systems above 1500L, 2020 - 2032
5.3 Single-Use Media Bags
5.3.1 Single-use media bags market estimates and forecast, 2020 - 2032
5.3.2 2D BAGS
5.3.2.1 Single-use media bags market estimates and forecast for 2D bags, 2020 - 2032
5.3.3 3D BAGS
5.3.3.1 Single-use media bags market estimates and forecast for 3D bags, 2020 - 2032
5.3.4 OTHERS
5.3.4.1 Single-use media bags market estimates and forecast for other bags, 2020 - 2032
5.4 Single-Use Filtration Assemblies
5.4.1 Single-use filtration assemblies market estimates and forecast, 2020 - 2032
5.5 Other products
5.5.1 Other single-use products market estimates and forecast, 2020 - 2032
Chapter 6 Single-Use Bioreactors Market: Type Business Analysis
6.1 Single-use bioreactors Market: Type Movement Analysis
6.2 Stirred-tank SUB
6.2.1 Stirred tank single-use bioreactors market estimates and forecast, 2020 - 2032
6.3 Wave-Induced SUB
6.3.1 Wave-induced single-use bioreactors market estimates and forecast 2020 - 2032
6.4 Bubble Column SUB
6.4.1 Bubble column single-use bioreactors market estimates and forecast, 2020 - 2032
6.5 Other SUB
6.5.1 Other single-use bioreactors market estimates and forecast, 2020 - 2032
Chapter 7 Single-Use Bioreactors Market: Type Of Cell Business Analysis
7.1 Single-use bioreactors Market: Type of Cell Movement Analysis
7.2 Mammalian Cell
7.2.1 Single-use bioreactors market estimates and forecast for mammalian cell, 2020 - 2032
7.3 Bacterial Cell
7.3.1 Single-use bioreactors market estimates and forecast for bacterial cell, 2020 - 2032
7.4 Yeast Cell
7.4.1 Single-use bioreactors market estimates and forecast for yeast cell, 2020 - 2032
7.5 Other Cells
7.5.1 Single-use bioreactors market estimates and forecast for other cells, 2020 - 2032
Chapter 8 Single-Use Bioreactors Market: Molecule Type Business Analysis
8.1 Single-use bioreactors Market: Molecule Type Movement Analysis
8.2 Monoclonal Antibodies
8.2.1 Single-use bioreactors market estimates and forecast for monoclonal antibodies, 2020 - 2032
8.3 Vaccines
8.3.1 Single-use bioreactors market estimates and forecast for vaccines, 2020 - 2032
8.4 Gene-Modified cells
8.4.1 Single-use bioreactors market estimates and forecast for gene modified cells, 2020 - 2032
8.5 Stem cells
8.5.1 Single-use bioreactors market estimates and forecast for stem cells, 2020 - 2032
8.6 Other molecules
8.6.1 Single-use bioreactors market estimates and forecast for other molecules, 2020 - 2032
Chapter 9 Single-Use Bioreactors Market: Application Business Analysis
9.1 Single-use bioreactors Market: Application Movement Analysis
9.2 Research And Development (R&D) Or Process Development
9.2.1 Single-use bioreactors market estimates and forecast for research & development, 2020 - 2032
9.3 Bioproduction
9.3.1 Single-use bioreactors market estimates and forecast for bioproduction, 2020 - 2032
Chapter 10 Single-Use Bioreactors Market: Usage Type Business Analysis
10.1 Single-use bioreactors Market: Usage Type Movement Analysis
10.2 Lab-Scale Production
10.2.1 Single-use bioreactors market estimates and forecast for lab-scale production, 2020 - 2032
10.3 Pilot-Scale Production
10.3.1 Single-use bioreactors market estimates and forecast for pilot-scale production, 2020 - 2032
10.4 Large-Scale Production
10.4.1 Single-use bioreactors market estimates and forecast for large-scale production, 2020 - 2032
Chapter 11 Single-Use Bioreactors Market: End-Use Business Analysis
11.1 Single-use bioreactors Market: End-use Movement Analysis
11.2 Pharmaceutical and Biopharmaceutical Companies
11.2.1 Single-use bioreactors market for pharmaceutical and biopharmaceutical companies, 2020 - 2032
11.3 CROs & CMOS
11.3.1 Single-use bioreactors market for CMOs AND CROs, 2020 - 2032
11.4 Academic and Research Institutes
11.4.1 Single-use bioreactors market for academic & research institutes, 2020 - 2032
Chapter 12 Single-Use Bioreactors Market: Regional Business Analysis
12.1 Single-use bioreactors Market: Regional Movement Analysis
12.2 North America
12.2.1 Swot Analysis
12.2.1.1 North America single-use bioreactors market, 2020 – 2032
12.2.2 U.S.
12.2.2.1 Key country dynamics
12.2.2.2 Competitive scenario
12.2.2.3 U.S. single-use bioreactors market, 2020 – 2032
12.2.3 Canada
12.2.3.1 Key Country Dynamics
12.2.3.2 Competitive Scenario
12.2.3.3 Canada Single-Use Bioreactors Market, 2020 – 2032
12.3 Europe
12.3.1 Swot Analysis
12.3.1.1 Europe Single-Use Bioreactors Market Estimates And Forecast, 2020 - 2032
12.3.2 Germany
12.3.2.1 Key Country Dynamics
12.3.2.2 Competitive Scenario
12.3.2.3 Germany Single-Use Bioreactors Market, 2020 - 2032
12.3.3 France
12.3.3.1 Key Country Dynamics
12.3.3.2 Competitive Scenario
12.3.3.3 France Single-Use Bioreactors Market, 2020 - 2032
12.3.4 Uk
12.3.4.1 Key Country Dynamics
12.3.4.2 Competitive Scenario
12.3.4.3 Uk Single-Use Bioreactors Market, 2020 - 2032
12.3.5 Italy
12.3.5.1 Key Country Dynamics
12.3.5.2 Competitive Scenario
12.3.5.3 Italy Single-Use Bioreactors Market, 2020 - 2032
12.3.6 Spain
12.3.6.1 Key Country Dynamics
12.3.6.2 Competitive Scenario
12.3.6.3 Spain Single-Use Bioreactors Market, 2020 - 2032
12.3.7 Denmark
12.3.7.1 Key Country Dynamics
12.3.7.2 Competitive Scenario
12.3.7.3 Denmark Single-Use Bioreactors Market, 2020 - 2032
12.3.8 Sweden
12.3.8.1 Key Country Dynamics
12.3.8.2 Competitive Scenario
12.3.8.3 Sweden Single-Use Bioreactors Market, 2020 - 2032
12.3.9 Norway
12.3.9.1 Key Country Dynamics
12.3.9.2 Competitive Scenario
12.3.9.3 Norway Single-Use Bioreactors Market, 2020 - 2032
12.4 Asia Pacific
12.4.1 Swot Analysis
12.4.1.1 Asia Pacific Vacuum Blood Collection Tube, 2020 - 2032
12.4.2 Japan
12.4.2.1 Key Country Dynamics
12.4.2.2 Competitive Scenario
12.4.2.3 Japan Single-Use Bioreactors Market, 2020 - 2032
12.4.3 China
12.4.3.1 Key Country Dynamics
12.4.3.2 Competitive Scenario
12.4.3.3 China Single-Use Bioreactors Market, 2020 - 2032
12.4.4 India
12.4.4.1 Key Country Dynamics
12.4.4.2 Competitive Scenario
12.4.4.3 India Single-Use Bioreactors Market, 2020 - 2032
12.4.5 Australia
12.4.5.1 Key Country Dynamics
12.4.5.2 Competitive Scenario
12.4.5.3 Australia Single-Use Bioreactors Market, 2020 - 2032
12.4.6 South Korea
12.4.6.1 Key Country Dynamics
12.4.6.2 Competitive Scenario
12.4.6.3 South Korea Single-Use Bioreactors Market, 2020 - 2032
12.4.7 Thailand
12.4.7.1 Key Country Dynamics
12.4.7.2 Competitive Scenario
12.4.7.3 Thailand Single-Use Bioreactors Market, 2020 - 2032
12.5 Latin America
12.5.1 Swot Analysis
12.5.1.1 Latin America Single-Use Bioreactors Market, 2020 - 2032
12.5.2 Brazil
12.5.2.1 Key Country Dynamics
12.5.2.2 Competitive Scenario
12.5.2.3 Brazil Single-Use Bioreactors Market, 2020 - 2032
12.5.3 Mexico
12.5.3.1 Key Country Dynamics
12.5.3.2 Competitive Scenario
12.5.3.3 Mexico Single-Use Bioreactors Market, 2020 - 2032
12.5.4 Argentina
12.5.4.1 Key Country Dynamics
12.5.4.2 Competitive Scenario
12.5.4.3 Argentina Single-Use Bioreactors Market, 2020 - 2032
12.6 Middle East & Africa (MEA)
12.6.1 Swot Analysis
12.6.1.1 MEA Single-Use Bioreactors Market Estimates And Forecast, 2020 - 2032
12.6.2 South Africa
12.6.2.1 Key Country Dynamics
12.6.2.2 Competitive Scenario
12.6.2.3 South Africa Single-Use Bioreactors Market Estimates And Forecast, 2020 - 2032
12.6.3 Saudi Arabia
12.6.3.1 Key Country Dynamics
12.6.3.2 Competitive Scenario
12.6.3.3 Saudi Arabia Single-Use Bioreactors Market Estimates And Forecast, 2020 - 2032
12.6.4 UAE
12.6.4.1 Key Country Dynamics
12.6.4.2 Competitive Scenario
12.6.4.3 UAE Single-Use Bioreactors Market Estimates And Forecast, 2020 - 2032
12.6.5 Kuwait
12.6.5.1 Key Country Dynamics
12.6.5.2 Competitive Scenario
12.6.5.3 Kuwait Single-Use Bioreactors Market Estimates And Forecast, 2020 - 2032
Chapter 13 Competitive Landscape
13.1 Participant’s Overview
13.1.1 Thermo Fisher Scientific Inc.
13.1.2 Sartorius Stedim Biotech
13.1.3 Merck Kgaa
13.1.4 Celltainer Biotech Bv.
13.1.5 Getinge Ab
13.1.6 Eppendorf Ag.
13.1.7 Cellexus
13.1.8 Pbs Biotech Inc.
13.1.9 Distek Inc.
13.1.10 Danaher Corporation
13.1.11 Abec
13.1.12 Able Corporation & Biott Corporation
13.1.13 G&G Technologies Inc.
13.1.14 Solida Biotech Gmbh
13.1.15 Satake Chemical Equipment Mfg., Ltd.
13.1.16 Stobbe Pharma Gmbh
13.1.17 Bbi-Biotech Gmbh
13.2 Financial Performance
13.3 Participant Categorization
13.3.1 Market Leaders
13.3.1.1 Single-Use Bioreactors Market Share Analysis, 2023
13.3.2 Strategy Mapping
13.3.2.1 Expansion
13.3.2.2 Acquisition
13.3.2.3 Collaborations
13.3.2.4 Product/service launch
13.3.2.5 Partnerships
13.3.2.6 Others
Cross-segment Market Size and Analysis for Mentioned Segments
Additional Company Profiles
(Upto 5 With No Cost)
Additional Countries (Apart
From Mentioned Countries)
Country/Region-specific Report
Go To Market Strategy
Region Specific Market DynamicsRegion Level Market Share Import Export AnalysisProduction AnalysisOthers