U.S. Cell Culture Market Size, Share & Trends Analysis Report By Product, By Application (Biopharmaceutical Production, Drug Development, Diagnostics, Tissue Culture & Engineering), And Segment) - Industry Analysis, Size, Share, Growth, Trends, and Forecast 2024-2033

U.S. Cell Culture Market Size and Growth

The U.S. cell culture market size was valued at USD 6.11 billion in 2023 and is projected to reach around USD 15.89 billion by 2033, registering a CAGR of 10.03% from 2024 to 2033.

U.S. Cell Culture Market Size, 2024 to 2033

U.S. Cell Culture Market Key Takeaways

  • The market is segmented into consumables and instruments. The consumables segment held the market with the largest revenue share of 58.98% in 2023.
  • The instruments segment is expected to register at a significant CAGR over the forecast period.
  • The biopharmaceutical production segment led the market with the largest revenue share of 31.87% in 2023 and is anticipated to grow at the fastest CAGR over the forecast period.
  • The diagnostics segment is expected to grow at a significant CAGR over the forecast period.

U.S. Cell Culture Market Growth 

The increasing frequency of chronic and infectious diseases (including COVID-19), the rapid adoption of cell culture techniques to develop substrates for safe viral vaccine manufacturing, and the expanding global demand for sophisticated therapeutic medical products have all contributed to market expansion. Furthermore, novel three-dimensional cell culture techniques and the growing need for them in biopharmaceutical development and vaccine production are likely to boost market expansion throughout the forecast period.

COVID-19 had a beneficial impact on the United States market. During the COVID-19 pandemic, many pharmaceutical and biotechnology companies have made significant investments in R&D to develop effective vaccinations, cures, and diagnostic kits. This has resulted in an increase in demand for cell culture techniques and novel cell-based models for drug development and research. Furthermore, due to the urgency of the situation, there has been an increase in the need for bioreactors and culture systems to facilitate vaccine production and drug testing.

Over the last few decades, biopharmaceutical goods such as vaccines, blood and blood components, somatic cells, gene therapy, tissues, and recombinant therapeutic proteins have grown in popularity in the life sciences industry. The need for biologics is expected to rise as specialty medications and personalized therapy become more prevalent. Furthermore, biologics play an important role in the creation of precision drugs. As a result, the US FDA authorized approximately 15 novel biologics in 2022, including cancer therapies such as Kimmtrak, Opdualag, Imjudo, and others.

The increasing demand for serum-free, specialty, and tailored media is expected to fuel market expansion. In addition, growing investment is expected to promote market growth throughout the forecast period. For example, Merck stated in July 2023 that it will expand its facilities in the United States to enhance production capacity for cell culture medium.

U.S. Cell Culture Market Report Scope

Report Attribute Details
Market Size in 2024 USD 6.72 Billion
Market Size by 2033 USD 15.89 Billion
Growth Rate From 2024 to 2033 CAGR of 10.03%
Base Year 2023
Forecast Period 2024 to 2033
Segments Covered Product, application
Market Analysis (Terms Used) Value (US$ Million/Billion) or (Volume/Units)
Report Coverage Revenue forecast, company ranking, competitive landscape, growth factors, and trends
Key Companies Profiled Sartorius AG; Danaher; Merck KGaA; Thermo Fisher Scientific, Inc.; Corning Inc.; Avantor, Inc.; BD; Eppendorf SE; Bio-Techne; PromoCell GmbH

U.S. Cell Culture Market Trends

  • Biopharmaceutical Industry Growth: The demand for cell culture products is closely tied to the biopharmaceutical industry. With the increasing development and approval of biologic drugs, there's a growing need for cell culture technologies to produce these complex therapeutics.
  • Shift towards Personalized Medicine: Personalized medicine, which tailors medical treatment to the individual characteristics of each patient, is becoming more prominent. Cell culture plays a crucial role in this field, particularly in the development of patient-specific cell therapies and in vitro diagnostic tools.
  • Rise in Stem Cell Research: Stem cell research is expanding rapidly, fueled by its potential applications in regenerative medicine, drug discovery, and disease modeling. This trend is boosting the demand for specialized cell culture media, reagents, and equipment tailored for stem cell culture.
  • Adoption of 3D Cell Culture: Traditional 2D cell culture systems are being replaced or complemented by more physiologically relevant 3D cell culture models. These models better mimic the complex microenvironment of living tissues, offering improved accuracy in drug testing and disease modeling.
  • Automation and High-throughput Technologies: Automation and robotics are increasingly integrated into cell culture workflows to improve efficiency, reproducibility, and scalability. High-throughput screening technologies enable the rapid screening of large compound libraries and cell-based assays, driving demand for automated cell culture systems.
  • Focus on Animal-Free and Serum-Free Culture Media: There's a growing emphasis on animal-free and serum-free cell culture media due to concerns about variability, contamination risks, and ethical considerations associated with traditional serum-based media. Manufacturers are developing and commercializing alternative formulations to meet this demand.
  • Rapid Growth of Cell-Based Therapies: The emergence of cell-based therapies, such as CAR-T cell therapy and gene therapy, is driving significant growth in the cell culture market. These therapies require large-scale expansion of patient-derived cells in culture, driving demand for specialized culture systems and media.
  • Emergence of Organ-on-a-Chip Technology: Organ-on-a-chip platforms, which simulate the structure and function of human organs on microfluidic chips, are gaining traction in drug discovery and toxicity testing. These platforms rely on cell culture techniques and are expected to drive demand for specialized culture systems and consumables.

U.S. Cell Culture Market By Product Insights

The market is segmented into consumables and instruments. The consumables segment held the market with the largest revenue share of 58.98% in 2023, due to recurring demand and purchase of consumables. Another factor propelling the sector is increased R&D expenditure by biotechnology & biopharmaceutical businesses to develop sophisticated biologics, such as monoclonal antibodies & vaccines. Consumables are expected to continue to be in high demand during the forecast period. The demand for cell culture consumables is also expected to remain high during the forecast period. The consumables segment is further categorized into reagents, media, & sera. Media held the largest market share in the consumables segment.

U.S. Cell Culture Market Share, By Product, 2023 (%)

The instruments segment is expected to register at a significant CAGR over the forecast period. The applications engaged are vaccination, research on cancer, drug screening & development, recombinant products, toxicity testing, stem cell technology, regenerative therapies, and other areas used by end-users, such as industrial, biotechnology, & agriculture. For instance, in June 2022, FUJIFILM Corporation invested USD 1.6 billion to expand and improve its cell culture manufacturing services. This investment would boost FUJIFILM sites in Denmark and Texas.

U.S. Cell Culture Market By Application Insights

Based on application, the market is segmented into biopharmaceutical production, drug development, diagnostics, tissue culture & engineering, cell and gene therapy, toxicity testing, and other applications. The biopharmaceutical production segment led the market with the largest revenue share of 31.87% in 2023 and is anticipated to grow at the fastest CAGR over the forecast period. Mammalian cell cultures are primarily used in the production of biopharmaceuticals, and the growing demand for nonconventional therapeutic options has led to a substantial increase in the bioproduction of genetically enhanced drugs. Due to this, demand for various cell culture consumables, such as media, is expected to increase.

The diagnostics segment is expected to grow at a significant CAGR over the forecast period. Cell cultures can be used in metabolomics for the identification of biomarkers of pathologically relevant conditions. Moreover, metabolic pathways that lead to the production of such biomarkers can also be identified to determine underlying metabolic disorders. Similarly, metabolites also play a crucial role in the diagnosis of cancer and its recurrence, which increases the scope of applications for cell culture products. Thus, this is expected to drive the market growth.

U.S. Cell Culture Market By Recent Developments

  • In May 2023, BD announced the global commercial launch of a new-to-the-world cell sorting equipment featuring two revolutionary innovations that allow researchers to reveal more comprehensive information regarding cells previously unseen in typical flow cytometry research
  • In March 2023, Danaher and the University of Pennsylvania announced a strategic alliance to advance cell therapy. The multi-year partnership aims to create new technologies, reduce delays in manufacturing, and provide next generation engineered cell products to patients with more consistent clinical outcomes
  • In February 2023, Thermo Fisher Scientific together with Celltrio announced a collaboration to provide clients in the biotherapeutics business with a fully controlled cell culture system
  • In February 2023, Corning Incorporated showcased its latest technology in automation & 3D cell culture at Society for Laboratory Automation & Screening (SLAS) conference in San Diego, California

U.S. Cell Culture Market Top Key Companies:

  • Sartorius AG
  • Danaher
  • Merck KGaA
  • Thermo Fisher Scientific, Inc.
  • Corning Inc.
  • Avantor, Inc.
  • BD
  • Eppendorf SE
  • Bio-Techne
  • PromoCell GmbH

U.S. Cell Culture Market Report Segmentation

This report forecasts revenue growth at country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2021 to 2033. For this study, Nova one advisor, Inc. has segmented the U.S. Cell Culture market.

By Product 

  • Consumables
      • Sera
        • Fetal Bovine Serum
        • Other
      • Reagents
        • Albumin
        • Others
      • Media
        • Serum-free Media
          • CHO Media
          • HEK 293 Media
          • BHK Medium
          • Vero Medium
          • Other Serum-free Media
          • Classical Media
          • Stem Cell Culture Media
          • Chemically Defined Media
          • Specialty Media
          • Other Cell Culture Media
    • Instruments
      • Culture Systems
      • Incubators
      • Centrifuges
      • Cryostorage Equipment
      • Pipetting

By Application 

  • Biopharmaceutical Production
    • Monoclonal Antibodies
    • Vaccines Production
    • Other Therapeutic Proteins
  • Drug Development
  • Diagnostics
  • Tissue Culture & Engineering
  • Cell & Gene Therapy
  • Toxicity Testing
  • Other Applications

Frequently Asked Questions

The U.S. cell culture market size was valued at USD 6.11 billion in 2023 and is projected to reach around USD 15.89 billion by 2033

The global U.S. cell culture market is expected to grow at a compound annual growth rate of 10.03% from 2024 to 2033

Based on product, the consumables segment held the largest market share of 58.0% in 2023, primarily due to recurring demand and purchase of consumables.

Some prominent players in the U.S. cell culture market include Sartorius AG; Danaher; Merck KGaA; Thermo Fisher Scientific, Inc.; Corning Inc.; Avantor, Inc.; BD; Eppendorf SE; Bio-Techne; PromoCell GmbH

Chapter 1. Methodology and Scope
                    1.1. Market Segmentation and Scope
                        1.1.1. Product Segment
                        1.1.2. Application Segment
                    1.2. Estimates and Forecast Timeline
                    1.3. Research Methodology
                    1.4. Information Procurement
                        1.4.1. Purchased Database
                        1.4.2. nova one advisor’s Internal Database
                        1.4.3. Primary Research
                    1.5. Information or Data Analysis:
                        1.5.1. Data Analysis Models
                    1.6. Market Formulation & Validation
                    1.7. Model Details
                        1.7.1. Commodity Flow Analysis
                    1.8. List of Secondary Sources
                    1.9. List of Abbreviations
                    1.10. Objective
Chapter 2. Executive Summary
                    2.1. Market Outlook
                    2.2. Segment Snapshot
                    2.3. Competitive Landscape Snapshot
Chapter 3. Market Variables &Trends
                    3.1. Market Lineage Outlook
                        3.1.1. Parent Market Outlook
                        3.1.2. Related/Ancillary Market Outlook
                    3.2. Market Dynamics
                        3.2.1. Market Driver Analysis
                            3.2.1.1. Expansion in the scope of applications for cell culture technology
                            3.2.1.2. Rising demand for biopharmaceuticals, artificial organs, & vaccine production
                            3.2.1.3. Growth in demand for serum-free, specialty, and customized media
                        3.2.2. Market Restraint Analysis
                            3.2.2.1. Stringent process control in cell culture techniques
                            3.2.2.2. Scalability issues with culturing methods
                            3.2.2.3. Ethical concerns regarding the use of animals
                    3.3. Industry Analysis Tools
                        3.3.1. Porter’s Five Forces Analysis
                        3.3.2. PESTEL Analysis
                        3.3.3. COVID-19 Impact Analysis
Chapter 4. Product Business Analysis
                    4.1. Product Segment Dashboard
                    4.2. U.S. Cell Culture Market Product Movement Analysis
                    4.3. U.S. Cell Culture Market Size & Trend Analysis, by Product, 2018 to 2030 (USD Million)
                    4.4. Consumables
                        4.4.1. Consumables market estimates and forecasts, 2021 - 2033
                        4.4.2. Sera
                            4.4.2.1. Sera market estimates and forecasts, 2021 - 2033
                            4.4.2.2. Fetal Bovine Serum
                                4.4.2.2.1. Fetal bovine serum market estimates and forecasts, 2021 - 2033
                            4.4.2.3. Other
                                4.4.2.3.1. Other market estimates and forecasts, 2021 - 2033
                        4.4.3. Reagents
                            4.4.3.1. Reagents market estimates and forecasts, 2021 - 2033
                            4.4.3.2. Albumin
                                4.4.3.2.1. Albumin market estimates and forecasts, 2021 - 2033
                            4.4.3.3. Other
                                4.4.3.3.1. Other market estimates and forecasts, 2021 - 2033
                        4.4.4. Media
                            4.4.4.1. Media market estimates and forecasts, 2021 - 2033
                            4.4.4.2. Serum-free Media
                                4.4.4.2.1. Serum-free media market estimates and forecasts, 2021 - 2033
                                4.4.4.2.2. CHO Media
                                    4.4.4.2.2.1. CHO media market estimates and forecasts, 2021 - 2033
                                4.4.4.2.3. HEK 293 Media
                                    4.4.4.2.3.1. HEK 293 media market estimates and forecasts, 2021 - 2033
                                4.4.4.2.4. BHK Medium
                                    4.4.4.2.4.1. BHK medium market estimates and forecasts, 2021 - 2033
                                4.4.4.2.5. Vero Medium
                                    4.4.4.2.5.1. Vero medium market estimates and forecasts, 2021 - 2033
                                4.4.4.2.6. Other Serum-free Media
                                    4.4.4.2.6.1. Other serum-free media market estimates and forecasts, 2021 - 2033
                            4.4.4.3. Classical Media
                                4.4.4.3.1. Classical media market estimates and forecasts, 2021 - 2033
                            4.4.4.4. Stem Cell Culture Media
                                4.4.4.4.1. Stem cell culture media market estimates and forecasts, 2021 - 2033
                            4.4.4.5. Chemically Defined Media
                                4.4.4.5.1. Chemically defined media market estimates and forecasts, 2021 - 2033
                            4.4.4.6. Specialty Media
                                4.4.4.6.1. Specialty media market estimates and forecasts, 2021 - 2033
                            4.4.4.7. Other Cell Culture Media
                                4.4.4.7.1. Other cell culture media market estimates and forecasts, 2021 - 2033
                    4.5. Instruments
                        4.5.1. Instruments market estimates and forecasts, 2021 - 2033
                        4.5.2. Culture Systems
                            4.5.2.1. Culture systems market estimates and forecasts, 2021 - 2033
                        4.5.3. Incubators
                            4.5.3.1. Incubators market estimates and forecasts, 2021 - 2033
                        4.5.4. Centrifuges
                            4.5.4.1. Centrifuges market estimates and forecasts, 2021 - 2033
                        4.5.5. Cryostorage Equipment
                            4.5.5.1. Cryostorage equipment market estimates and forecasts, 2021 - 2033
                        4.5.6. Biosafety Equipment
                            4.5.6.1. Biosafety equipment market estimates and forecasts, 2021 - 2033
                        4.5.7. Pipetting
                            4.5.7.1. Pipetting market estimates and forecasts, 2021 - 2033
Chapter 5. Application Business Analysis
                    5.1. Application Segment Dashboard
                    5.2. U.S. Cell Culture Market Application Movement Analysis
                    5.3. U.S. Cell Culture Market Size & Trend Analysis, by Application, 2018 to 2030 (USD Million)
                    5.4. Biopharmaceutical Production
                        5.4.1. Biopharmaceutical production market estimates and forecasts, 2021 - 2033
                        5.4.2. Monoclonal Antibodies
                            5.4.2.1. Monoclonal antibodies market estimates and forecasts, 2021 - 2033
                        5.4.3. Vaccine Production
                            5.4.3.1. Vaccine production market estimates and forecasts, 2021 - 2033
                        5.4.4. Other Therapeutic Proteins
                            5.4.4.1. Other therapeutic proteins market estimates and forecasts, 2021 - 2033
                    5.5. Drug Development
                        5.5.1. Drug development market estimates and forecasts, 2021 - 2033
                    5.6. Diagnostics
                        5.6.1. Diagnostics market estimates and forecasts, 2021 - 2033
                    5.7. Tissue Culture and Engineering
                        5.7.1. Tissue culture and engineering market estimates and forecasts, 2021 - 2033
                    5.8. Cell & Gene Therapy
                        5.8.1. Cell & gene therapy market estimates and forecasts, 2021 - 2033
                    5.9. Toxicity Testing
                        5.9.1. Toxicity testing market estimates and forecasts, 2021 - 2033
                    5.10. Other Application
                        5.10.1. Other applications market estimates and forecasts, 2021 - 2033
Chapter 6. Competitive Landscape
                    6.1. Company Categorization
                    6.2. Strategy Mapping
                    6.3. Company Market Position Analysis, 2023
                    6.4. Company Profiles/Listing
                        6.4.1. Sartorius AG
                            6.4.1.1. Overview
                            6.4.1.2. Financial Performance
                            6.4.1.3. Product Benchmarking
                            6.4.1.4. Strategic Initiatives
                        6.4.2. Danaher
                            6.4.2.1. Overview
                            6.4.2.2. Financial Performance
                            6.4.2.3. Product Benchmarking
                            6.4.2.4. Strategic Initiatives
                        6.4.3. Merck KGaA
                            6.4.3.1. Overview
                            6.4.3.2. Financial Performance
                            6.4.3.3. Product Benchmarking
                            6.4.3.4. Strategic Initiatives
                        6.4.4. Thermo Fisher Scientific, Inc.
                            6.4.4.1. Overview
                            6.4.4.2. Financial Performance
                            6.4.4.3. Product Benchmarking
                            6.4.4.4. Strategic Initiatives
                        6.4.5. Corning Inc.
                            6.4.5.1. Overview
                            6.4.5.2. Financial Performance
                            6.4.5.3. Product Benchmarking
                            6.4.5.4. Strategic Initiatives
                        6.4.6. Avantor Inc.
                            6.4.6.1. Overview Avantor Inc.
                            6.4.6.2. Financial Performance
                            6.4.6.3. Product Benchmarking
                            6.4.6.4. Strategic Initiatives
                        6.4.7. BD
                            6.4.7.1. Overview
                            6.4.7.2. Financial Performance
                            6.4.7.3. Product Benchmarking
                            6.4.7.4. Strategic Initiatives
                        6.4.8. Eppendorf SE
                            6.4.8.1. Overview
                            6.4.8.2. Financial Performance
                            6.4.8.3. Product Benchmarking
                            6.4.8.4. Strategic Initiatives
                        6.4.9. Bio-Techne
                            6.4.9.1. Overview
                            6.4.9.2. Financial Performance
                            6.4.9.3. Product Benchmarking
                            6.4.9.4. Strategic Initiatives
                        6.4.10. PromoCell GmbH
                            6.4.10.1. Overview
                            6.4.10.2. Financial Performance
                            6.4.10.3. Product Benchmarking
                            6.4.10.4. Strategic Initiatives

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